Epicuresmo, Stoicism and skepticism:
For Epicurus, happiness is the absence of pain and maximum pleasure. This is achieved, and that man is mortal yslo have this material life, denying the fear of the gods, by denying the fear of death and no fear to fate, as the wise man seeks to adapt their lives to the laws of nature and thereby manages to avoid the fear of random, since it is the philosopher, as the ideal wise man, looking to meet Nature and its laws and how to live according to them.
The Stoic policy:
This moral doctrine states that the human soul is part of the Logos or Universal Reason and that the soul is material and corprea. Virtue, understood as a means to achieve that harmony which the Universal Reason submits all, should reject the superfluous, unnecessary and unreasonable. Life is interpreted as a struggle, and in this fight, right is rational. The sage, free from emotions and passions, get tico ideal of apathy, that is, the liberation for pleasure.
Seneca is the representative in Rome of the moral doctrine that will have an enormous influence on Christianity. 
The three periods of Stoicism, starting with the Zenn to Citium, described as the ideal tico: indifference elusive, in the case of Posidonius, delivery and Seneca hopeful, resigned compliance.